Many AWS operations return paginated results when the response object is too large for a single response. Boto3 provides pagination methods for seamless iteration of results across service calls.

Boto3 provides helper methods called waiters, which automatically poll for predefined status changes in AWS resources. For example, you can start an Amazon EC2 instance and use a waiter to wait until it reaches the 'running' state, or you can create a new Amazon DynamoDB table and wait until it is available to use. Boto3 has waiters for both client and resource APIs.

Boto3 comes with many features that are service-specific, such as automatic multi-part transfers for Amazon S3 and simplified query conditions for Amazon DynamoDB.